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Bioorg Med Chem Lett. 2005 Jul 15;15(14):3333-7.

Synthesis of cationic beta-vinyl substituted meso-tetraphenylporphyrins and their in vitro activity against herpes simplex virus type 1.

Author information

1
Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.

Abstract

An easy route to cationic beta-vinyl substituted meso-tetraphenylporphyrin derivatives is described. Two novel compounds were tested in vitro for their antiviral photoactivity against herpes simplex virus type 1. One of these compounds exhibited a significant activity, reaching 99% of virus inactivation after 15 min of photoactivation.

PMID:
15951174
DOI:
10.1016/j.bmcl.2005.05.044
[Indexed for MEDLINE]

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