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Am J Cardiol. 2005 Jun 15;95(12):1518-21.

Transcatheter patch occlusion of perimembranous ventricular septal defects.

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Athenian Institute of Pediatric Cardiology, Athens, Greece.


Sixteen surgical candidates for ventricular septal defect correction were brought to the catheterization laboratory for transcatheter patch occlusion. There were 3 cases of nonrestrictive ventricular septal defects, including 2 with malalignment (tetralogy of Fallot). All patients, except those with tetralogy of Fallot who were cyanotic, had large left-right shunts. They were all corrected through the femoral vein. All defects with the exception of 2 were successfully occluded (12 full occlusions, 2 residual shunts). On follow-up, there were no embolizations, aortic insufficiency, or other complications. The method appears effective and relatively safe, and could challenge the current surgical standard of treatment.

[Indexed for MEDLINE]

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