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Respir Med. 2005 Aug;99(8):1004-9. Epub 2005 Apr 12.

Body composition by bioelectrical impedance predicts mortality in chronic obstructive pulmonary disease patients.

Author information

1
Department of Clinical Nutrition, Institute of Internal Medicine, Sahlgrenska Academy at Göteborg University, P.O. Box 459, 405 30 Göteborg, Sweden. frode.slinde@nutrition.gu.se

Abstract

Pulmonary rehabilitation is recommended in international treatment guidelines for chronic obstructive pulmonary disease (COPD). No one has however studied the effect on long-term mortality. The aim of the current study was to study the mortality in a sample of patients with severe COPD included in a 1-year multidisciplinary rehabilitation program. Body composition was assessed at baseline using bioelectrical impedance. Mortality was studied in 86 patients using the Cox proportional hazards model. Forty-seven (55%) of the patients died during the mean follow-up time which was almost 6 years. Risk of mortality increased with increasing age, increasing number of hospital days the year before inclusion and men had higher mortality risk than women. The mortality risk decreased with increasing % reference body weight, increasing fat-free mass index (FFMI), increasing FEV(1) and increasing 6-min walking distance. Gender, age and FFMI continued to be statistical significant predictors of mortality when controlling for the other baseline variables in a multivariate analysis. To conclude, body composition, measured by bioelectrical impedance and presented as FFMI, is an independent predictor of mortality in COPD patients.

PMID:
15950141
DOI:
10.1016/j.rmed.2004.09.024
[Indexed for MEDLINE]
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