Format

Send to

Choose Destination
See comment in PubMed Commons below
Neuron. 2005 May 19;46(4):523-5.

Reluctant vesicles coaxed into the limelight.

Author information

1
Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Abstract

Synapses respond to brief, repetitive stimulation with synaptic depression when initial transmitter release probability is high. Vesicle depletion has been a long-standing hypothesis for depression, but results unexplained by the depletion hypothesis have been nagging. In this issue of Neuron, Xu and Wu show that, under some conditions, calcium current inactivation explains stimulus-dependent depression at the calyx of Held.

PMID:
15944119
DOI:
10.1016/j.neuron.2005.05.003
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center