Format

Send to

Choose Destination
Pediatr Emerg Care. 2005 Jun;21(6):359-62.

Budesonide offers no advantage when added to oral dexamethasone in the treatment of croup.

Author information

1
Emergency Department, Princess Margaret Hospital for Children, Perth, WA, Australia. Gary.Geelhoed@health.wa.gov.au

Abstract

OBJECTIVE:

To evaluate the effect of adding inhaled budesonide (2 mg) to oral dexamethasone 0.15 mg/kg in children hospitalized with croup.

SETTING:

Observation ward of a Tertiary Paediatric Hospital Emergency Department.

SUBJECTS:

Seventy-two children (age range 3 to 126 months) hospitalized with croup.

INTERVENTION:

Children randomized to receive either 2 mg of nebulized budesonide or placebo, with all children receiving a single oral dose of 0.15 mg/kg dexamethasone.

OUTCOME MEASURES:

Primary outcome was duration of hospital stay. Other measures included croup scores from 0 to 12 hours, use of nebulized epinephrine, duration of croup symptoms, duration of viral symptoms, and return to medical care for croup or for any other reason following discharge from hospital.

RESULTS:

Baseline characteristics for the 2 groups were similar. There was no difference in time to discharge for the 2 groups or for other outcome measures with a risk ratio of 1.3 (95% confidence intervals of 0.82 and 2.1).

CONCLUSIONS:

The addition of inhaled budesonide (2 mg) to oral dexamethasone (0.15 mg/kg) offers no advantage in the treatment of children hospitalized with croup.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wolters Kluwer
Loading ...
Support Center