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Dev Cell. 2005 Jun;8(6):803-16.

Polarity proteins in axon specification and synaptogenesis.

Author information

1
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

Abstract

The neuron is a prime example of a highly polarized cell. It is becoming clear that conserved protein complexes, which have been shown to regulate polarity in such diverse systems as the C. elegans zygote and mammalian epithelia, are also required for neuronal polarization. This review considers the role of these polarity proteins in axon specification and synaptogenesis.

PMID:
15935771
DOI:
10.1016/j.devcel.2005.05.007
[Indexed for MEDLINE]
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