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Trends Genet. 2005 Jul;21(7):413-20.

Cell cycle and cell-fate determination in Drosophila neural cell lineages.

Author information

1
Institut Jacques Monod, CNRS, University Paris 6 and 7, 2 Place Jussieu, 75005 Paris, France.

Abstract

"Normal" development requires a finely tuned equilibrium between cell differentiation and cell proliferation. Important issues in development include whether the cell cycle controls the cell-fate determination and whether cell identity in turn regulates cell-cycle progression. Although, these issues are of general biological relevance, stereotyped Drosophila neural lineages are particularly suited to address these questions and have provided insights into the links between cell-cycle progression and cell-fate specification.

PMID:
15927300
DOI:
10.1016/j.tig.2005.05.010
[Indexed for MEDLINE]

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