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Mutat Res. 2005 Sep 4;577(1-2):92-117.

'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system.

Author information

1
Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, 111 Alexander Drive, MD D3-01, Research Triangle Park, NC 27709, USA.

Abstract

DNA damage recognition represents a long-standing problem in the field of protein-DNA interactions. This article reviews our current knowledge of how damage recognition is achieved in bacterial nucleotide excision repair through the concerted action of the UvrA, UvrB, and UvrC proteins.

PMID:
15927210
DOI:
10.1016/j.mrfmmm.2005.03.013
[Indexed for MEDLINE]

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