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Toxicon. 2005 Jun 15;45(8):1041-9. Epub 2005 Apr 19.

Platelets as targets of snake venom metalloproteinases.

Author information

1
Department of Haematology, University of Liverpool, Daulby Street, Liverpool L69 3GA, UK. aurakami@liverpool.ac.uk

Abstract

For centuries snake venoms have been known to interfere with haemostasis and this is now known basically due either to toxins activating/inhibiting clotting factors, having effects on blood vessels or interfering with platelet function. In this short review, the interaction of one major group of toxins, the snake venom metalloproteinases, with platelets is considered. This is relevant for understanding the mechanism of haemorrhage induced by these toxins.

PMID:
15922773
DOI:
10.1016/j.toxicon.2005.02.026
[Indexed for MEDLINE]

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