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Trends Cell Biol. 2005 Jul;15(7):343-5.

Bacterial DNA segregation by the actin-like MreB protein.

Author information

1
Department of Biochemistry and Molecular Biology, Campusvej 55, University of Southern Denmark, DK-5230 Odense M, Denmark.

Abstract

Faithful chromosome segregation is vital to all organisms. Eukaryotic cells use the tubulin-based cytoskeleton to segregate their chromosomes during mitosis. A handful of papers have provided convincing evidence that, in bacteria, this task is accomplished by the actin homolog MreB. In particular, a recent study by Gitai et al. demonstrates that MreB specifically binds to and segregates the replication origin of the bacterial chromosome.

PMID:
15922599
DOI:
10.1016/j.tcb.2005.05.002
[Indexed for MEDLINE]

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