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Trends Parasitol. 2005 Jun;21(6):273-7.

Tissue migration by parasitic helminths - an immunoevasive strategy?

Author information

1
Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. grace.mulcahy@ucd.ie

Abstract

Migration through host tissues has major costs for parasitic helminths in terms of energy expenditure, risks of attrition and the need to adapt to varying physicochemical environments. Nevertheless, such migratory phases seem to confer a specific survival advantage. One reason for this might be the avoidance of specific host immune-defence mechanisms designed to protect against threats at mucosal surfaces.

PMID:
15922248
DOI:
10.1016/j.pt.2005.04.003
[Indexed for MEDLINE]
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