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Antimicrob Agents Chemother. 2005 Jun;49(6):2510-1.

In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosis.

Author information

1
Department of Pediatrics, Columbia University, 622 West 168th St., PH4W-470, New York, NY 10032, USA.

Abstract

Doripenem 50% inhibitory concentrations (MIC50) and 90% inhibitory concentrations (MIC90) for multidrug-resistant strains of mucoid Pseudomonas aeruginosa (n=200 strains), nonmucoid P. aeruginosa (n=200), and Burkholderia cepacia complex (n=200) isolated from patients with cystic fibrosis were 8 and 32, 8 and 64, and 8 and 32 microg/ml, respectively. Doripenem had somewhat better activity than established antimicrobial agents.

PMID:
15917558
PMCID:
PMC1140534
DOI:
10.1128/AAC.49.6.2510-2511.2005
[Indexed for MEDLINE]
Free PMC Article

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