The results reported in this article are from a larger, mixed-methods study of the factors influencing the preparedness of adult daughters for taking care of elderly parents. This article focuses on findings surfacing in unstructured interviews with daughters revealing an area of caregiving not addressed in survey items, that of daughters' emotional reactions to multiple losses. Actual and anticipatory losses clustered into two categories: loss of the parent and loss of one's own youth. Implications for health care providers are detailed, including: recognizing each daughter's unique life situation; providing anticipatory and long-term emotional support and counseling; and assisting with problem solving, grief work, and making meaning of losses.