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Cleft Palate Craniofac J. 1992 May;29(3):246-53.

Robin sequence: changes in thinking leading to changes in patient care.

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Center for Craniofacial Disorders, Montefiore Medical Center, Bronx, NY 10467.


Robin sequence is now understood to be a grouping of clinical findings that does not represent a distinct multiple anomaly syndrome. Previously known as the "Pierre Robin syndrome," this fairly common association of micrognathia with cleft palate and upper airway obstruction was initially thought to be a specific disease, and entire treatment regimens were established to deal with presumed problems. Until recently, the management of Robin has not been excellent and mortality has been high. It is only a better understanding of the basic mechanisms leading to this sequence that has resulted in better care. This article reviews the history of the delineation of Robin sequence and how the perception of Robin has led directly to management decisions.

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