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Biochemistry. 1992 May 26;31(20):4737-49.

Bile acid biosynthesis.

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  • 1Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235.


To conclude, the last several years have seen a resurgence of interest in the biosynthesis of bile acids. This focus has come about due to the central roles that these molecules play in cholesterol and fat metabolism and due to recent advances in their chemistry, biochemistry, and molecular biology. The application of probes generated by these methodologies has begun to generate novel insight into bile acid metabolism, regulation, and genetics. The next several years should be equally exciting.

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