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Neurology. 2005 May 24;64(10):1807-9.

Effect of pravastatin on cerebral infarcts and white matter lesions.

Author information

1
Department of Internal Medicine, Leiden University Medical Center, The Netherlands. V.H.ten_Dam@lumc.nl

Abstract

The authors examined the effect of pravastatin 40 mg daily on the progression of ischemic brain lesions using repeated brain MRI. After a mean treatment period of 33 months, there was an increase in total ischemic lesion load of 1.1 cm3 (p < 0.001) in the 270 placebo-treated subjects and 1.1 cm3 (p < 0.001) in the 265 pravastatin-treated subjects. There was no difference between the two treatment groups (p = 0.73).

[Indexed for MEDLINE]

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