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Neurology. 2005 May 24;64(10):1775-7.

Patients with ALS can use sensorimotor rhythms to operate a brain-computer interface.

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Institute of Medical Psychology and Behavioral Neurobiology, Eberhard-Karls University Tübingen, Tübingen, Germany.


People with severe motor disabilities can maintain an acceptable quality of life if they can communicate. Brain-computer interfaces (BCIs), which do not depend on muscle control, can provide communication. Four people severely disabled by ALS learned to operate a BCI with EEG rhythms recorded over sensorimotor cortex. These results suggest that a sensorimotor rhythm-based BCI could help maintain quality of life for people with ALS.

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