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J Child Adolesc Psychopharmacol. 2005 Apr;15(2):331-3.

Atomoxetine use associated with onset of a motor tic.

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Department of Psychiatry and Pediatrics, University of Oklahoma-Tulsa, Tulsa, Oklahoma 74135, USA.


Patients with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for Tourette's Disorder and other tic disorders. Stimulant medications and bupropion have been associated with the onset or exacerbation of a tic disorder. The selective norepinephrine reuptake inhibitor, atomoxetine, has been proposed to be an alternative medication for patients with ADHD and a comorbid tic disorder. This paper reviews a case study in which the onset of a motor tic was associated with a trial of the medication atomoxetine. Further research is needed to determine if atomoxetine is an appropriate alternative medication in patients with ADHD and a comorbid tic disorder.

[Indexed for MEDLINE]

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