Format

Send to

Choose Destination
Monaldi Arch Chest Dis. 2004 Oct-Dec;61(4):209-12.

Evaluation of co-morbidity indices in patients admitted for chronic obstructive pulmonary disease.

Author information

1
General Internal Medicine, University of Vermont, Burlington 05401, USA. richard.pinckney@vtmednet.org

Abstract

BACKGROUND:

There is limited and conflicting information on the use of co-morbidity instruments to predict mortality in patients with chronic obstructive pulmonary disease (COPD).

METHODS:

We sought to test the validity of the Charlson Index and another co-morbidity instrument, the Adult co-morbidity evaluation 27 (ACE-27), in patients admitted with COPD exacerbations. Co-morbidity scores were obtained by chart review. Information on mortality was retrieved from the Social Security Death Index. We examined the predictive validity of the Charlson and the ACE-27 using survival analysis.

RESULTS:

There were 112 patients eligible for the study. The ACE-27 but not the Charlson predicted survival, after adjusting for age, gender, and smoking history in Cox regression, hazard ratio (95% CI) of 1.99 (1.17-3.39).

CONCLUSIONS:

This study confirms earlier findings that the Charlson Index is not a reliable predictor of mortality in patients with COPD. However, the ACE-27 appears to be useful for predicting survival in this study.

PMID:
15909610
DOI:
10.4081/monaldi.2004.683
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center