Format

Send to

Choose Destination
See comment in PubMed Commons below
Cell. 2005 May 20;121(4):495-6.

Ro's role in RNA reconnaissance.

Author information

1
Howard Hughes Medical Institute, Department of Molecular & Cell Biology, Lawrence Berkeley National Laboratory, University of California at Berkeley, Berkeley, CA 94720, USA.

Abstract

The Ro 60 kDa autoantigen binds misfolded RNAs and likely functions in small RNA quality control. In this issue of Cell, Stein et al. (2005) present crystal structures of Ro alone and bound to both double- and single-stranded RNA, revealing two distinct RNA binding sites that suggest how Ro may distinguish between native and misfolded small RNAs.

PMID:
15907458
DOI:
10.1016/j.cell.2005.05.004
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center