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Am J Dermatopathol. 2005 Jun;27(3):237-9.

Follicular acantholysis: a subtle clue to the early diagnosis of pemphigus vulgaris.

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1
Quest Diagnostics Incorporated, Cambridge, Massachusetts, USA. mahalinm@questdiagnostics.com

Abstract

The histologic hallmark of fully established pemphigus vulgaris (PV), a chronic autoimmune disease of the skin and mucosa, is the presence of acantholysis induced at the suprabasal level. This case report of acantholysis restricted to the follicular epithelium as a subtle histologic manifestation of the disease, draws attention to the pitfalls encountered in the histologic diagnosis of early cases of pemphigus vulgaris.

PMID:
15900129
[Indexed for MEDLINE]
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