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Mutat Res. 2005 Jun 6;583(2):184-8.

Cell type-specific genotoxic effects of intermittent extremely low-frequency electromagnetic fields.

Author information

1
Division of Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

Abstract

The issue of adverse health effects of extremely low-frequency electromagnetic fields (ELF-EMFs) is highly controversial. Contradictory results regarding the genotoxic potential of ELF-EMF have been reported in the literature. To test whether this controversy might reflect differences between the cellular targets examined we exposed cultured cells derived from different tissues to an intermittent ELF-EMF (50 Hz sinusoidal, 1 mT) for 1-24h. The alkaline and neutral comet assays were used to assess ELF-EMF-induced DNA strand breaks. We could identify three responder (human fibroblasts, human melanocytes, rat granulosa cells) and three non-responder cell types (human lymphocytes, human monocytes, human skeletal muscle cells), which points to the significance of the cell system used when investigating genotoxic effects of ELF-EMF.

PMID:
15899587
DOI:
10.1016/j.mrgentox.2005.03.011
[Indexed for MEDLINE]

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