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Microbes Infect. 2005 May;7(5-6):939-46. Epub 2005 Apr 15.

Improved protection by recombinant BCG.

Author information

1
Department of Immunology, Max-Planck Institute for Infection Biology, Schumannstr. 21/22, 10117 Berlin, Germany.

Abstract

Mycobacterium bovis bacille Calmette Guérin (BCG) is one of the most widely used live vaccines. Technologic advancement in genome manipulation enables the construction of recombinant BCG (rBCG) strains, which can be employed as highly immunogenic vaccines against tuberculosis with improved safety profile.

PMID:
15890553
DOI:
10.1016/j.micinf.2005.03.012
[Indexed for MEDLINE]

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