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Cancer. 2005 Jun 15;103(12):2435-46.

Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma.

Author information

1
Department of Medicine, University of California-San Francisco, San Francisco, California 94115, USA. venhook@cc.ucsf.edu

Abstract

Substantial effort has focused on the development of novel targeted agents for treating patients with late-stage colorectal carcinoma. These agents are designed specifically to inhibit biochemical processes associated with pathogenesis. Numerous molecules targeting the epidermal growth factor receptor have been investigated as therapeutic agents and appear to herald a shift in the treatment paradigm for colorectal carcinoma.

PMID:
15880563
DOI:
10.1002/cncr.21123
[Indexed for MEDLINE]
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