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Dent Mater. 2005 Sep;21(9):831-6.

A triclosan-containing compomer reduces Lactobacillus spp. predominant in advanced carious lesions.

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Center of Dental Medicine, Policlinic of Operative Dentistry and Periodontology, University of Cologne, Kerpener Str. 32, D-50931 Köln, Germany.



To assess the antimicrobial effect of acid etching or a triclosan-containing compomer on the cultivable microflora of incompletely excavated dentinal carious lesions.


Thirty detinal lesions were opened with a diamond burr. Subsequent to removal of the softened biomass a sample of dentin was taken from the cavity floor with a round bur. Ten cavities each were treated with 36% phosphoric acid (PH) for 15s, covered with a triclosan-containing compomer (TC) or received no treatment as control (CO). All lesions were restored with a compomer composite. Sampling was performed directly after etching in the PH group and at re-entry after 6 weeks in all groups. Aliquots were plated on blood agar and selective media for Lactobacilli (Rogosa) and mutans Streptococci (MSB). Cultures were incubated anaerobically for 7 days at 37 degrees C prior to quantitative assessment and biotyping of the isolates.


Application of phosphoric acid resulted in initial reduction of the totally cultivable microflora (p=0.006). Evaluation of the total number of cultivable microflora after 6 weeks revealed no differences between the groups (p>0.05). Lactobacilli counts were significantly lower in the TC group compared to the PH and CO groups (p<0.05). No difference was detected between the PH and CO groups after 6 weeks.


Phosphoric acid initially reduces the number of microorganisms in carious dentin but not in the longer term. The experimental triclosan composite suppresses Lactobacilli species over a period of 6 weeks.

[Indexed for MEDLINE]

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