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Br J Cancer. 2005 May 23;92(10):1834-6.

A prospective longitudinal study of performance status, an inflammation-based score (GPS) and survival in patients with inoperable non-small-cell lung cancer.

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1
University Department of Surgery, Royal Infirmary, Glasgow G31 2ER, UK.

Abstract

The value of an inflammation-based prognostic score (Glasgow Prognostic score, GPS) was compared with performance status (ECOG-ps) in a longitudinal study of patients (n=101) with inoperable non-small-cell lung cancer (NSCLC). At diagnosis, stratified for treatment, only the GPS (HR 2.32, 95% CI 1.52-3.54, P<0.001) was a significant predictor of survival. In contrast, neither the GPS nor ECOG-ps measured at 3-6 months follow-up were significant predictors of residual survival. This study confirms the prognostic value of the GPS, at diagnosis, in patients with inoperable NSCLC. However, the role of the GPS and ECOG-ps during follow-up has not been established.

PMID:
15870712
PMCID:
PMC2361776
DOI:
10.1038/sj.bjc.6602591
[Indexed for MEDLINE]
Free PMC Article

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