Thyroid disease in a rural Kenyan hospital

East Afr Med J. 2004 Dec;81(12):631-3. doi: 10.4314/eamj.v81i12.9248.

Abstract

Objectives: To review the spectrum of thyroid pathology diagnoses likely to be encountered by surgeons working in East African hospitals.

Design: A retrospective review of all thyroidectomies performed over a three year period.

Setting: A rural church based hospital in Kenya.

Subjects: Two hundred and twenty two patients who underwent thyroidectomy over a three year period at Kijabe hospital.

Interventions: A simple protocol was used to manage thyroid disease involving history, clinical examination, measurement of TSH and needle aspiration of lesions where appropriate, and excision when clinically indicated.

Main outcome measures: Clinical diagnosis, tribe, operation performed, pathology, and complications of surgery.

Results: Two hundred and twenty thyroidectomies were performed. Overall there was a malignancy rate of 11.7% (15 papillary, 11 follicular). The commonest pathological diagnosis was multinodular goitre (47%). Graves' disease was a relatively common diagnosis in this series (13%). The mortality rate was 0.5% and the morbidity rate was 3.6%.

Conclusion: Graves' disease is not as uncommon in rural Africa as previously thought. Malignancy is relatively common and there appears to be a change in the papillary to follicular cancer ratio perhaps reflecting widespread iodinisation of salt in Kenya.

MeSH terms

  • Adenoma / epidemiology
  • Adenoma / surgery
  • Female
  • Goiter / epidemiology
  • Goiter / surgery
  • Hospitals, Rural / statistics & numerical data*
  • Humans
  • Kenya / epidemiology
  • Male
  • Retrospective Studies
  • Thyroid Diseases / epidemiology*
  • Thyroid Diseases / surgery*
  • Thyroid Neoplasms / epidemiology
  • Thyroid Neoplasms / surgery
  • Thyroidectomy / statistics & numerical data*