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Childs Nerv Syst. 2006 Feb;22(2):189-92. Epub 2005 Apr 30.

Successful treatment of multiple Pseudallescheria boydii brain abscesses and ventriculitis/ependymitis in a 2-year-old child after a near-drowning episode.

Author information

1
Department of Neurosurgery, Zentralklinik, Robert-Koch Allee 9, 99438, Bad Berka, Germany.

Abstract

RATIONALE:

We report on a cerebral infection by Pseudallescheria boydii in a 21-month-old boy after a near-drowning episode. MRI revealed multiple (> 60) intracerebral abscesses.

METHODS:

The surgical therapy included CSF drainage and microsurgical resection of one abscess for microbiological diagnosis. Antimycotic therapy included terbinafine and intraventricular caspofungin in addition to voriconazole.

RESULTS:

Systemic side effects of chemotherapy were not observed. After placement of a ventriculoperitoneal shunt, the boy was transferred to a rehabilitation clinic and improved neurologically. After 20 months, MRI documented a continuing remission of the disease.

CONCLUSION:

Our case proves that an aggressive treatment should be undertaken and can be successful in CNS pseudallescheriasis.

PMID:
15864705
DOI:
10.1007/s00381-005-1151-3
[Indexed for MEDLINE]

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