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J Am Acad Dermatol. 2005 May;52(5):793-7.

Large or multiple congenital melanocytic nevi: occurrence of cutaneous melanoma in 1008 persons.

Author information

1
info@nevusnetwork.org

Abstract

BACKGROUND:

There is a dearth of information regarding the occurrence of cutaneous melanoma in a large cohort of persons with large congenital melanocytic nevi (LCMN) or multiple congenital melanocytic nevi (MCMN).

OBJECTIVE:

The purpose of this article is to report our experience with 1008 persons having LCMN and MCMN.

METHODS:

Information was evaluated that was obtained from a database of persons with LCMN or MCMN voluntarily submitted by the affected persons to a nevus support group, the Nevus Network.

RESULTS:

Of those with garment LCMN, 2.9% developed cutaneous melanoma associated with 0.8% deaths. Of those with LCMN on the head or extremity, 0.3% developed cutaneous melanoma associated with no deaths to date. Of the small number with MCMN without a giant nevus, 6.7% developed cutaneous melanoma.

LIMITATIONS:

Attending physician confirmation of submitted information was unavailable. Conclusions LCMN and MCMN were associated with a low occurrence of cutaneous melanoma in our group.

PMID:
15858468
DOI:
10.1016/j.jaad.2005.02.024
[Indexed for MEDLINE]
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