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Postgrad Med. 2005 Apr;117(4):29-30, 33-5, 39 passim.

Taking aim at HDL-C. Raising levels to reduce cardiovascular risk.

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  • 1Kos Pharmaceuticals.


Although statin therapy has revolutionized management of coronary heart disease (CHD), the lowering of low-density lipoprotein cholesterol (LDL-C) levels is not the whole story. Increased plasma concentrations of high-density lipoprotein cholesterol (HDL-C) have a cardioprotective effect that is just as important for reducing risk of heart attack and stroke. In this article, Dr McGovern examines the evidence that provides the rationale for HDL-C as a therapeutic target for cardiovascular risk reduction.

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