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Intensive Care Med. 2005 Jun;31(6):859-64. Epub 2005 Apr 19.

A new device for administration of continuous positive airway pressure in preterm infants: comparison with a standard nasal CPAP continuous positive airway pressure system.

Author information

1
Pediatric Department, Medical School, Padua University, Via Giustiniani 3, 35158 Padua, Italy. trevo@pediatria.unipd.it

Abstract

OBJECTIVE:

We compared the effectiveness of a new continuous positive airway pressure (CPAP) device (neonatal helmet CPAP) with a conventional nasal CPAP system in preterm neonates needing continuous distending pressure.

DESIGN AND SETTING:

Randomized, physiological, cross-over study in a tertiary referral, neonatal intensive care unit in a university teaching hospital.

PATIENTS:

Twenty very low birth weight infants with a postnatal age greater than 24 h who were receiving nasal CPAP for apnea and/or mild respiratory distress were enrolled.

INTERVENTIONS:

CPAP delivered by neonatal helmet CPAP and nasal CPAP in random order for two subsequent 90-min periods.

MEASUREMENTS AND RESULTS:

Were continuously measured the Neonatal Infant Pain Scale (NIPS) score, oxygen requirements, respiratory rate, heart rate, oxygen saturation, transcutaneous PO(2) (tcPO(2)) and PCO(2) (tcPCO(2)), blood pressure, and desaturations. NIPS scores were significantly lower when the infants were on the neonatal helmet CPAP than when they were on nasal CPAP (0.26+/-0.07 vs. 0.63+/-0.12). The other studied parameters did not differ between the two CPAP modes. The number of desaturations was reduced during the neonatal helmet CPAP treatment (18 vs. 32), although this difference was not significant.

CONCLUSIONS:

In this short-term physiological study the neonatal helmet CPAP appears to be as good as the golden standard for managing preterm infants needing continuous distending pressure, with enhanced tolerability. Further evaluation in a randomized clinical trial is needed to confirm these findings.

PMID:
15838676
DOI:
10.1007/s00134-005-2638-9
[Indexed for MEDLINE]

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