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Mol Cell. 2005 Apr 15;18(2):143-5.

Regulation of Akt/PKB Ser473 phosphorylation.

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1
School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland.

Abstract

For years the Akt/PKB research field has been in turmoil, trying to understand how the activating phosphorylation of Akt/PKB at Ser473 is regulated. In the past month, papers in a recent issue of Molecular Cell (Gao et al., 2005) and in Science (Sarbassov et al., 2005) may have identified the phosphatase and kinase acting on this residue.

PMID:
15837416
DOI:
10.1016/j.molcel.2005.03.020
[Indexed for MEDLINE]
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