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Mol Cell Endocrinol. 2005 Apr 29;234(1-2):81-6.

Anti-Müllerian hormone and folliculogenesis.

Author information

1
Department of Internal Medicine, Section of Endocrinology, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. j.visser@erasmusmc.nl

Abstract

This paper reviews the role of anti-Müllerian hormone, a member of the TGF(beta) family signaling through a BMP-like pathway, in the ovary. In vivo and in vitro studies showed that AMH has an inhibitory effect on primordial follicle recruitment and it decreases the sensitivity of follicles for the FSH-dependent selection for dominance. Besides its functional role in the ovary, AMH serum level serves as an excellent candidate marker of ovarian reserve.

PMID:
15836956
DOI:
10.1016/j.mce.2004.09.008
[Indexed for MEDLINE]

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