Send to

Choose Destination
Naturwissenschaften. 2005 Jun;92(6):293-6. Epub 2005 Apr 16.

Hormetic protection of Drosophila melanogaster middle-aged male flies from heat stress by mildly stressing them at young age.

Author information

Centre de Recherche sur la Cognition Animale, UMR CNRS 5169, Université Paul-Sabatier, 118 route de Narbonne, F-31062, Toulouse cedex 4, France.


Previous studies have shown that exposing flies to hypergravity (3g or 5g) for the first 2 weeks of adult life slightly increases longevity of male flies and survival time at 37 degrees C for both sexes, and delays an age-linked behavioral change. The present experiment tested whether the hypergravity could also protect flies from four successive deleterious non-lethal heat shocks at 4 and 5 weeks of age. Males that lived in hypergravity for the first 2 weeks of adult life lived slightly longer (ca. +15% or 1.2 day) after heat shocks (30 min or 45 min at 37 degrees C) than flies that always lived at 1g, but this positive effect of hypergravity was not observed in females. Therefore, hypergravity exposure at young age can help the male flies recovering from a heat shock at older ages.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center