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Emerg Infect Dis. 2005 Apr;11(4):572-8.

European bat lyssavirus in Scottish bats.

Author information

1
World Health Organization Collaborating Centre for the Characterisation of Rabies and Rabies-Related Viruses, Surrey, United Kingdom.

Abstract

We report the first seroprevalence study of the occurrence of specific antibodies to European bat lyssavirus type 2 (EBLV-2) in Daubenton's bats. Bats were captured from 19 sites across eastern and southern Scotland. Samples from 198 Daubenton's bats, 20 Natterer's bats, and 6 Pipistrelle's bats were tested for EBLV-2. Blood samples (N = 94) were subjected to a modified fluorescent antibody virus neutralization test to determine antibody titer. From 0.05% to 3.8% (95% confidence interval) of Daubenton's bats were seropositive. Antibodies to EBLV-2 were not detected in the 2 other species tested. Mouth swabs (N = 218) were obtained, and RNA was extracted for a reverse transcription-polymerase chain reaction (RT-PCR). The RT-PCR included pan lyssavirus-primers (N gene) and internal PCR control primers for ribosomal RNA. EBLV-2 RNA was not detected in any of the saliva samples tested, and live virus was not detected in virus isolation tests.

PMID:
15829196
PMCID:
PMC3320325
DOI:
10.3201/eid1104.040920
[Indexed for MEDLINE]
Free PMC Article

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