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Arch Phys Med Rehabil. 2005 Apr;86(4):626-32.

Efficacy of a physical therapy program in patients with Parkinson's disease: a randomized controlled trial.

Author information

1
Sargent College of Health and Rehabilitation Sciences, Department of Rehabilitation Sciences and Center for Neurorehabilitation, Boston University, MA 02215, USA. tellis@bu.edu

Abstract

OBJECTIVE:

To investigate the effects of a physical therapy (PT) program in groups of people with Parkinson's disease (PD).

DESIGN:

Randomized controlled trial with a crossover design.

SETTING:

Two outpatient rehabilitation clinics in Boston and Amsterdam, respectively.

PARTICIPANTS:

Sixty-eight subjects diagnosed with typical, idiopathic PD, Hoehn and Yahr stage II or III, and stable medication use.

INTERVENTION:

Group A received PT and medication therapy (MT) for the first 6 weeks, followed by MT only for the second 6 weeks. Group B received only MT for the first 6 weeks and PT and MT for the second 6 weeks.

MAIN OUTCOME MEASURES:

The Sickness Impact Profile (SIP-68), the mobility portion of the SIP-68, the Unified Parkinson's Disease Rating Scale (UPDRS), and comfortable walking speed (CWS) at baseline, 6-week, 12-week, and 3-month follow-up.

RESULTS:

At 6 weeks, differences between groups were significant for the SIP mobility ( P =.015; effect size [ES]=.55), for CWS ( P =.012; ES=.49), for the activities of daily living (ADL) section of the UPDRS ( P =.014; ES=.45), and for the total UPDRS ( P =.007; ES=.56). The total SIP and the mentation and motor sections of the UPDRS did not differ significantly between groups. Significant differences were found at 3 months compared with baseline for CWS, the UPDRS ADL, and total scores.

CONCLUSIONS:

People with PD derive benefits in the short term from PT group treatment, in addition to their MT, for quality of life related to mobility, CWS, and ADLs; long-term benefits were found in CWS, UPDRS ADL, and total scores but varied between groups.

PMID:
15827910
DOI:
10.1016/j.apmr.2004.08.008
[Indexed for MEDLINE]

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