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Microbes Infect. 2005 Apr;7(4):776-88. Epub 2005 Mar 16.

Role of CD8+ T lymphocytes in control of Mycobacterium tuberculosis infection.

Author information

1
Department of Molecular Microbiology and Immunology, Oregon Health and Science University 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

Abstract

Tuberculosis remains a global health concern. Control of infection is dependent on cell-mediated immune responses, with CD4+ T lymphocytes playing a central role. In this article, data supporting the importance of CD8+ T lymphocytes is reviewed, with an emphasis on the unique functional roles that this lymphocyte subset may play.

PMID:
15823514
DOI:
10.1016/j.micinf.2005.03.001
[Indexed for MEDLINE]

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