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Immunol Today. 1992 Apr;13(4):122-5.

Tumor necrosis factor alpha in autoimmunity: pretty girl or old witch?

Author information

1
Dept of Inflammation Biology and Immunology, Syntex Research, Palo Alto, CA 94303.

Abstract

The role of TNF-alpha in the pathogenesis of autoimmune disorders is poorly understood. Evidence in favor of a pathogenic role has come mainly from in vitro experiments, while in vivo studies in animal models have suggested a protective role. In this article, Chaim Jacob attempts to reconcile these apparently contradictory studies.

PMID:
1580993
DOI:
10.1016/0167-5699(92)90107-i
[Indexed for MEDLINE]

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