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Phytother Res. 2005 Jan;19(1):54-7.

Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale (Catuama) in healthy volunteers.

Author information

1
Miguel Servet Clinical Pharmacology Unit, 415 JesuĂ­no Marcondes Machado Avenue, Campinas, SP 13092-320, Brazil. oliveira_ch@terra.com.br

Abstract

In Brazil, a herbal medicinal extract named Catuama containing a mixture of Paullinia cupana (guarana; Sapindaceae), Trichilia catigua (catuaba; Meliaceae), Ptychopetalum olacoides (muirapuama; Olacaceae) and Zingiber officinale (ginger; Zingiberaceae) is used as a body stimulant, energetic, tonic and aphrodisiac. The present study investigated the chronic administration of 25 mL Catuama twice a day during 28 days for any toxic effect on healthy human volunteers of both sexes. No severe adverse reactions or haematological and biochemical changes were reported.

PMID:
15798997
DOI:
10.1002/ptr.1484
[Indexed for MEDLINE]

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