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Arch Pathol Lab Med. 2005 Apr;129(4):507-10.

Three-dimensional virtual microscopy of colorectal biopsies.

Author information

1
Department of Pathology, University of California, Irvine School of Medicine, Irvine, USA. mlwu@uci.edu

Abstract

Conventional optical microscopy of specimens from colorectal biopsies commonly produces diagnostic errors due to incomplete sampling or poor orientation. Obtaining additional sections or re-embedding may help avoid these errors, but can prolong turnaround time. We describe new technology, which incorporates exhaustive sectioning, 3-dimensional reconstruction, and virtual microscopy, that may eliminate these problems by enabling pathologists to rapidly examine entire specimens and convert poorly oriented mucosa to well-oriented mucosa.

[Indexed for MEDLINE]

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