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Otol Neurotol. 2005 Mar;26(2):135-9.

Efficacy of the KTP laser in the treatment of middle ear cholesteatoma.

Author information

1
Department of Otolaryngology, Gloucestershire Hospitals Trust, Gloucester, UK. john.hamilton@dial.pipex.com

Abstract

OBJECTIVE:

To evaluate whether ancillary use of the KTP (potassium titanyl phosphate) laser can diminish the rate of residual disease in intact canal wall cholesteatoma surgery.

STUDY DESIGN:

Prospective controlled parallel group study.

SETTING:

Two neighboring district general hospitals, one with a KTP laser and one without.

PATIENTS:

All patients undergoing staged intact canal wall surgery for cholesteatoma.

INTERVENTION:

Staged intact canal wall surgery for cholesteatoma.

MAIN OUTCOME MEASURE:

Presence or absence of residual disease at the second stage operation, performed at least 12 months after the first operation.

RESULTS:

Thirty-three patients underwent treatment without and 36 underwent treatment with the laser. Ten patients without laser treatment had residual disease, whereas one patient had residual disease after laser treatment (p = 0.003). After adjustment using logistic regression, treatment still has a significant effect on outcome (p = 0.013). The number needed to treat is four.

DISCUSSION:

Ancillary use of the KTP laser in cholesteatoma surgery is a treatment that significantly improves complete removal of disease.

PMID:
15793394
[Indexed for MEDLINE]

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