Late isolated brain metastasis following enucleation for choroidal melanoma

Ophthalmic Surg Lasers Imaging. 2005 Mar-Apr;36(2):151-4.

Abstract

Brain metastases from choroidal melanoma are rare and usually have a grave prognosis. A case of successfully treated late isolated brain metastasis from choroidal melanoma is described. A 35-year-old man presented with epileptic seizures of recent origin, 9 years following enucleation for choroidal melanoma. Imaging studies revealed a lesion of the right frontal lobe that was surgically removed. Results of pathologic examination were compatible with metastatic choroidal melanoma. The patient is asymptomatic 5 years postoperatively. Late isolated brain metastases from uveal melanoma may be treatable by local resection. Close, lifelong follow-up is required to diagnose and aggressively treat metastatic disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiography, Digital Subtraction
  • Brain Neoplasms / diagnosis
  • Brain Neoplasms / secondary*
  • Brain Neoplasms / surgery
  • Choroid Neoplasms / diagnostic imaging
  • Choroid Neoplasms / pathology*
  • Choroid Neoplasms / surgery
  • Diagnosis, Differential
  • Eye Enucleation*
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Angiography
  • Male
  • Melanoma / diagnosis
  • Melanoma / secondary*
  • Melanoma / surgery
  • Reoperation
  • Time Factors
  • Tomography, X-Ray Computed