Format

Send to

Choose Destination
Evolution. 2005 Jan;59(1):24-37.

Gene tree distributions under the coalescent process.

Author information

1
Department of Mathematics and Statistics, University of New Mexico, Albuquerque, New Mexico 87131, USA. james@stat.unm.edu

Abstract

Under the coalescent model for population divergence, lineage sorting can cause considerable variability in gene trees generated from any given species tree. In this paper, we derive a method for computing the distribution of gene tree topologies given a bifurcating species tree for trees with an arbitrary number of taxa in the case that there is one gene sampled per species. Applications for gene tree distributions include determining exact probabilities of topological equivalence between gene trees and species trees and inferring species trees from multiple datasets. In addition, we examine the shapes of gene tree distributions and their sensitivity to changes in branch lengths, species tree shape, and tree size. The method for computing gene tree distributions is implemented in the computer program COAL.

PMID:
15792224
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center