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Mol Divers. 2005;9(1-3):141-7.

Myxobacterial epothilones and tubulysins as promising anticancer agents.

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  • 1R&D Biopharmaceuticals, München, Germany. alexander.doemling@t-online.de

Abstract

Tubulin-binding agents play a pivotal role in current cancer therapy and there are many efforts in pre-clinical and clinical development of known and novel cytotoxic agents ongoing. In this article a known class, epothilones, as well as a novel class, tubulysins, are presented.

PMID:
15789561
[PubMed - indexed for MEDLINE]
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