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Org Lett. 2005 Mar 31;7(7):1375-8.

Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria.

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  • 1College of Pharmacy, Oregon State University, Corvallis, Oregon 97331, USA.

Abstract

[structure: see text] Chemical investigation of two field collections of marine cyanobacteria has led to the discovery of two new cytotoxic natural products, ankaraholides A (2) and B (3), along with the known compound swinholide A (1). Since swinholide-type compounds were previously localized to the heterotrophic bacteria of sponges, these findings raise intriguing questions about their true metabolic source.

PMID:
15787510
DOI:
10.1021/ol050188x
[PubMed - indexed for MEDLINE]
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