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J Addict Dis. 2005;24(2):91-106.

Methadone maintenance and male sexual dysfunction.

Author information

1
University of Wisconsin Medical Schoool, Department of Family Medicine, Madison, WI 53715, USA. Randy.Brown@fammed.wisc.edu

Abstract

PURPOSE:

This study reports the prevalence and types of sexual dysfunction in a sample of men on methadone maintenance for opioid dependence, and describes factors which may contribute to sexual dysfunction.

METHODS:

92 opioid-dependent men were recruited from a methadone maintenance clinic and completed two questionnaires, a research interview and laboratory measures.

RESULTS:

Fourteen percent reported some sexual dysfunction. Erectile dysfunction (r = 0.24, p = 0.020), libido dysfunction (r = 0.30, p = 0.003), and global dysfunction (r = 0.26, p = 0.013) increased with increasing age of the patient. Methadone dose showed a significant direct correlation with increased orgasm dysfunction, both before and after adjusting for duration of treatment (p = 0.012). None of the sexual dysfunction subscales or global dysfunction were associated with plasma testosterone or plasma prolactin levels.

CONCLUSIONS:

The rate of global sexual dysfunction in methadonetreated men is similar to general population studies and should be evaluated using general population guidelines. Orgasm dysfunction is a special case and may respond to methadone dose reduction.

PMID:
15784526
DOI:
10.1300/J069v24n02_08
[Indexed for MEDLINE]

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