Format

Send to

Choose Destination
See comment in PubMed Commons below
Head Neck. 2005 Jun;27(6):494-502.

F-18 FDG PET-CT fusion in radiotherapy treatment planning for head and neck cancer.

Author information

1
Department of Radiation Oncology, Division of Nuclear Medicine and Molecular Imaging, Emory Clinic and Emory University, Atlanta, Georgia, USA.

Abstract

BACKGROUND:

The fusion of fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) with CT scans has been shown to improve diagnostic accuracy and staging in non-small cell lung cancer. We report on the influence of PET-CT fusion on the management of patients with head and neck cancer.

METHODS:

Thirty-six patients with intact primary head and neck cancers treated with radiation therapy (RT) received PET-CT as part of treatment planning. Workup before PET-CT included a contrast-enhanced CT scan of the head and neck and chest X-ray; patients with nasopharyngeal and paranasal sinus primary tumors also underwent MRI.

RESULTS:

Changes in TNM score and American Joint Committee on Cancer stage occurred in 13 patients (36%) and five patients (14%), respectively, based on PET-CT. RT volume and dose were altered in five patients (14%) and four patients (11%), respectively. Five patients initially were seen with carcinoma of unknown primary, and PET-CT confirmed oropharyngeal primary tumors in two. PET-CT data also detected a synchronous lung cancer in one patient.

CONCLUSION:

PET-CT fusion may have a significant impact on staging and determination of RT treatment volume and dose.

PMID:
15772951
DOI:
10.1002/hed.20179
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center