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Pediatr Blood Cancer. 2005 Jul;45(1):64-7.

Anaplastic transformation from papillary thyroid carcinoma with increased serum CA19-9.

Author information

1
Department of Pediatrics, Mie University School of Medicine, Tue, Mie 514-8507, Japan. ogwmshr@yahoo.co.jp

Abstract

A 24-year-old woman presented with anaplastic transformation from papillary thyroid carcinoma with increased serum CA19-9. The patient had been diagnosed as having papillary thyroid carcinoma with lung metastasis at 11 years of age. She received a total thyroidectomy with cervical lymph node dissection followed by iodine-131 ((131)I) therapy over 12 years, but died due to sudden onset of rapid dissemination. Elevated serum CA19-9 was detected in the terminal stage, and anaplastic transformation was confirmed by post-mortem examination. Although there are few clinical reports suggesting a prognostic indicator for anaplastic thyroid carcinoma, CA19-9 may be a useful serum marker for this tumor.

PMID:
15770642
DOI:
10.1002/pbc.20375
[Indexed for MEDLINE]

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