Format

Send to

Choose Destination
See comment in PubMed Commons below
J Clin Invest. 2005 Mar;115(3):565-71.

Death begets failure in the heart.

Author information

1
Department of Medicine, Cardiovascular Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

Abstract

Recently, low--but abnormal--rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.

PMID:
15765138
PMCID:
PMC1052022
DOI:
10.1172/JCI24569
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Society for Clinical Investigation Icon for PubMed Central
    Loading ...
    Support Center