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Br J Cancer. 2005 Mar 14;92(5):891-4.

High viral loads of human papillomavirus predict risk of invasive cervical carcinoma.

Author information

1
Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala 751 85, Sweden.

Abstract

High loads of human papillomavirus (HPV) 16 and HPV 18/45 increase the risk of developing invasive cervical carcinoma, revealing higher risk in percentiles of highest viral loads for HPV 16 (odds ratio (OR) 58.7, 95% confidence interval (CI) 21.9-151.4) compared to HPV 18/45 (OR 3.3, 95% CI 1.5-7.2). Thus, HPV load is a type-dependent risk marker for invasive carcinoma.

PMID:
15756259
PMCID:
PMC2361906
DOI:
10.1038/sj.bjc.6602436
[Indexed for MEDLINE]
Free PMC Article

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